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KMID : 0359720160340040384
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Journal of the Korean Neurological Association
2016 Volume.34 No. 4 p.384 ~ p.387
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Ischemic Stroke with Extracranial Internal Carotid Artery Occlusion in Essential Thrombocythemia with JAK-2 Mutation
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Lee Jee-Eun
Jung A-Reum
Choi Ji-Hyun
Kim Tae-Kyung
Kwon Eun-Jin
Lee Chan-Young
Chun Min-Young
Chang Yoon-Kyung
Kim Yong-Jae
Song Tae-Jin
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Abstract
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In essential thrombocythemia (ET), cerebral infarction with large cerebral artery occlusion has rarely been reported. A 53-year-old male was admitted with left sided weakness. Brain magnetic resonance images revealed right internal carotid artery (ICA) territory infarction and proximal ICA occlusion. The blood laboratory examination demonstrated continuously increased platelet count (above 617,000/μL). Increased megakaroycytes and JAK2 V617F mutation were confirmed in the bone marrow biopsy. We should consider the possibility of ET in patient with large artery thrombosis and thrombocythemia.
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KEYWORD
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Thrombocythemia, Essential, Cerebral infarction, Janus kinase 2
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